About the Book
A comprehensive reference survey on the identification and development of promising cancer chemopreventive agents that will help stimulate further novel research and new approvable drugs. For each agent, the authors review the relevant mechanisms of action, the criteria for populations benefiting from intervention, the safety and pharmacodynamics, clinical study design emphasizing the use of precancers, and early associated cellular and molecular biomarkers of carcinogenesis. The pharmacologic and/or mechanistic classes discussed range from antimutagens, antiinflammatories, and the nuclear receptor superfamily, to signal transduction modulators, antioxidants, vitamins, and minerals. The overall focus is on molecular targets and mechanisms. A second volume, Strategies in Chemoprevention, describes the exciting methodologies that will accelerate progress in this field and discusses the state of clinical development of chemoprevention in the various human cancer target organs.
Book Details
ISBN-13: 9781588290762
EAN: 9781588290762
Publisher Date: 04 Jun 2004
Dewey: 616.994
Illustration: Y
LCCN: 2004000342
No of Pages: 697
Series Title: English
Width: 219 mm
ISBN-10: 158829076X
Publisher: Humana Press
Binding: Hardcover
Height: 280 mm
Language: English
MediaMail: Y
PrintOnDemand: Y
Spine Width: 44 mm
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