About the Book
The first part of the book gives basic information on epidemiology, pathogenesis and classification of diabetic retinopathy.
The second part shows how to read, interpret fluorescein angiography, classic cross-section OCT, en-face OCT, and the most common OCT angiography, documenting and diagnosing the different features of background, non-proliferative and proliferative diabetic retinopathy.
Discusses most recent typical and atypical aspects of imaging and modern treatment.
Develop understanding in fluorescein angiography, OCT and OCT angiography in clinical work.
It will show the practical interest of clinical imaging and treatment in everyday ophthalmology.
About the Author
Bruno Lumbroso MD
Marco Rispoli MD
Maria Cristina Savastano MD PhD
Table of Contents: Chapter 1 Diabetes 1
Chapter 2 Diabetic Retinopathy 2
Incidence and Prevalence 2
Prevalence 3
Epidemiology 3
Prognosis 3
Treatment 3
Chapter 3 Classification 4
Chapter 4 Pathogenesis of Diabetic Retinopathy 5
Exudation 6
Lesions in Vessel Walls 6
Changes in Blood Flow 8
Ischemia 8
Alterations in the Platelets 8
Alterations in the Arterioles 10
Vegf-Proliferation of New Vessels 10
Genetic Factors 10
Chapter 5 Pathophysiology of Diabetic Retinopathy 20
Incipient Retinopathy: Elementary Lesions 22
Chapter 6 Diabetic Retinopathy Natural evolution 22
Nonproliferative Exudative Retinopathy 31
Advanced Retinopathy 37
Proliferative Retinopathy 45
Diabetic Maculopathy 49
Ischemic Maculopathy 50
Chapter 7 Retinal fluoroangiography 56
Interpretation of the Fluoroangiography in Diabetic Retinopathy 57
Analysis of Fluoroangiography: Elementary Abnormalities 57
Hyperfluorescence: Due to Leakage 59
Hyperfluorescence: Staining 61
Hyperfluorescence: Pooling 64
Hypofluorescence 65
Hypofluorescence due to Vascular Filling Defects 66
Imaging overview of fluoroangiography in diabetic retinopathy 67
Chapter 8 OCT in Diabetic Retinopathy 74
Oct in Nonproliferative Diabetic Retinopathy 74
Elementary Lesions 75
Progression of Nonproliferative Diabetic Retinopathy 84
Oct in Proliferative Retinopathy 84
Traction Retinal Detachment 84
Contents
viii Diabetic Retinopathy
Chapter 9 OCT Angiography 88
Incipient Diabetic Retinopathy 88
Background Diabetic Retinopathy 89
Chapter 10 Diabetic Retinopathy Treatment 92
Prevention 92
Medical Treatment of Diabetic Retinopathy 92
Laser Treatment 92
Complications due to Laser Treatment 94
Surgical Treatment 94
Antiangiogenic Treatment 95
Vitrectomy 95
Index 97