This revised edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the disorders that result from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject, and this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and its role in ageing and gender-specific effects. This compilation by the world's leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. The volume is the most authoritative, comprehensive and detailed account available and will be an essential source of reference for all endocrinologists.