The past several years have witnessed a dramatic increase in the development and use of in vitro systems in pharmacology and toxicology. This volume consists of information on all major in vitro models which have been developed and are currently being used to identify and study toxic and pharmacological phenomena. These models include methods for isolating and culturing cells, tissue slices, and perfused organs for the liver, kidney, lung and heart. The advantages and disadvantages for each model are examined closely and examples of how each model is used are also provided. Toxicologists, pharmacologists, and biochemists will find this book to be a useful addition to their reference collection.