This research studied low pressure(LP), low pressure-high-output (LPHO, medium pressure(MP) and pulsed (PUV) UV Systems and their effects on various pathogens. Among the findings were: bacteria is more susceptible to UV light than viruses; some strains of E.coli had different dose responses without explanation; adenovirus serotypes 40 and 41 are highly resistant to UV inactivation and a residual disinfection process is recommended to follow UV disinfection. All details of the study and models are discussed thoroughly.