Integrative medicine is the integration of evidence-based complementary and alternative therapies into mainstream health care with the goals of optimizing health promotion, preventing disease, improving patient outcomes, managing symptoms, and improving quality of life. The guest editors have assembled expert authors who present state-of-the-art articles on topics including nutritional supplements, acupuncture, mind-body therapies, massage therapy, and evidence-based botanical research. Other articles address ethical issues and providing integrative care in a major cancer center.