This book provides a state-of-the-art overview of mechanical circulatory support devices and their role in the care of patients with advanced heart failure. It is targeted at healthcare teams around the world who are involved with the patient care, research and teaching in advanced heart failure, those in training, and the interested lay public. Situations in which a patient with advanced heart failure is evaluated as well as cared for before and after implantation of mechanical circulatory support devices have to be described in a complementary way by professional teams and their patients. Therefore, these perspectives are presented alongside to provide a comprehensive overview of the process of care in its entire scope. In particular, evidence-based medicine perspectives of expert cardiologists, cardiac surgeons, nurses, coordinators, social workers, psychologists, physical therapists, and equally important, of our patients and their relatives, are portrayed.