Describes recent advances in reduction, including the use of boron- and aluminum-based hydride reagents, as well as catalytic hydrogenation methods. Reports applications of reduction procedures with emphasis on selectivity, ranging from chemoselective to enantioselective reductions. Offers chapters on different aspects of reduction and presents a complementary mix of academic and industrial research ranging from theory to practical applications. Includes an overview chapter with 200 references by Nobel laureate H.C. Brown that surveys the development of hydride reduction in organic chemistry over the past 60 years.