Step-Up to the Bedside, Second Edition is a comprehensive case-based review book for the USMLE Step 1 and Step 2 CS. It presents 100 clinical cases following the USMLE format and focuses on the basic science underlying each clinical scenario. The case-based presentation helps students assimilate and synthesize basic science information and provides excellent preparation for USMLE Step 1, USMLE Step 2 CS, and clinical clerkships. This edition contains thirty completely new cases, and all existing cases have been extensively updated. Each case now opens with learning objectives and ends with USMLE-style questions. Quick Hits bullets, mnemonics, figures, and tables help readers retain information. Fifty of the cases will be available online.